Accelerating
biomedical research and assays in Health
& Wellbeing
At AVICEMIS, we are revolutionizing the way research labs conduct biological analysis with C. elegans, one of the most significant animal models in biomedical studies. Traditionally, experiments involving C. elegans have relied heavily on manual handling and inspection by skilled experts, often making the process labor-intensive and time-consuming. Our innovative automated analysis system changes this paradigm by streamlining and accelerating these procedures.
Designed with cutting-edge artificial vision technology,
Our machine automates the complex tasks of sorting, analyzing, and processing C. elegans, allowing researchers to focus on deeper scientific inquiries while increasing throughput and precision. By enabling labs to scale their experiments more efficiently, we are helping to drive critical advances in health and wellbeing research, from disease modeling to drug discovery, ultimately contributing to societal progress and improved healthcare outcomes.
What is C. elegans
C. elegans, a small nematode about 1 mm in length, has emerged as a highly promising model in biological research, particularly in drug development and the study of diseases. This organism is incredibly cost-effective to maintain and can be grown in large quantities in laboratories, making it an efficient option for high-volume research.
What makes C. elegans an exceptional model is the extensive scientific knowledge surrounding it: its genome has been fully mapped and sequenced. Despite its simplicity, it shares many tissues and organs with more complex organisms, such as the nervous system, digestive tract, muscles, and reproductive system. Its transparent anatomy allows these systems to be monitored in vivo throughout its life cycle—less than three weeks—using non-invasive optical methods.
Additionally, C. elegans exhibits behaviors that are highly influenced by its environment and experiences, making it an ideal model for neuroscience, behavioral biology, and toxicology studies. Its exquisite sensitivity to environmental conditions and remarkable behavioral plasticity have positioned it as a key tool in the search for solutions to human diseases and the evaluation of new drugs.
Due to these characteristics, C. elegans has emerged as one of the premiere model systems in many research fields, including aging, neurobiology, and even rudimentary forms of learning. The ease with which C. elegans can be grown, manipulated, and observed has driven research into new areas, making this tiny nematode a silent collaborator in three Nobel Prizes and thousands of research articles over the past years. Future developments in optical methods will continue to enrich our knowledge and understanding of how biological pathways orchestrate development, learning, memory, behavior, and aging.
Compliance with good practices in C. elegans assays is essential for reliable results. Key factors such as temperature, humidity, pH, and worm density have a significant impact on growth, lifecycle, and gene expression.
Proper management of these variables helps avoid unwanted variations, such as epigenetic changes, stress-resistant dauer larvae, and issues like genetic drift. Furthermore, precise control is needed when working with solid or liquid media, E. coli feeding, and the presence of males in populations to prevent interference with outcomes. The integration of automated systems like AVICEMIS, leveraging robotics, computer vision, and artificial intelligence, simplifies C. elegans workflows, significantly enhancing efficiency and profitability by minimizing risks associated with these variables.
AVICEMIS: Your Best Investment in Innovation
Investing in innovation is crucial for the growth and success of your company. Avicemis offers you the technological solution you need to achieve your goals.
Contact us to discover how we can help you develop high-tech computer vision and automation that provide you with a sustainable competitive advantage.
Together, we can shape the future of your industry and make a lasting impact on the world.